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Copyright © 2012 American Chemical Society
September 3, 2012 Cover
Volume 90, Issue 36
Volume 90, Issue 36
Increasingly discouraged by genomics-based discovery, researchers revert to whole-cell screening for tuberculosis treatments
Credit: Atul Loke/TB Alliance
» Full Article
September 3, 2012 Issue
Volume 90, Issue 36
September 3, 2012 Issue, Vol. 90 | Iss. 36
Increasingly discouraged by genomics-based discovery, researchers revert to whole-cell screening for tuberculosis treatments
(pp. 15-24)
Features
Government & Policy
Mapping Nanotech Drugs’ Landscape
FDA struggles to identify products, optimize review process (pp. 46-48)
Science & Technology
Extracting Uranium From Seawater
ACS Meeting News: Massive marine supply of metal drives researchers to design selective, durable sorbents (pp. 60-63)
A Nonprofit Network For Tuberculosis Drugs
Developing a drug for a neglected disease economically involves wide-reaching partnerships
(pp. 26-27)
Neglected Diseases: K-RITH Puts Cutting-Edge Research At The Heart Of HIV-TB Epidemic
(pp. 22-23)
News of the Week
Membrane Separates Oil And Water With Ease
Materials: Hydrophilic-oleophobic combo could clean up oil spills
(p.9)
Costly Setbacks For Big Pharma
Pharmaceuticals: Bristol-Myers Squibb, Eli Lilly & Co. halt work on drug candidates
(p.10)
Victory For Stem Cell Research
Policy: Court affirms legality of federally funded research on human embryonic stem cells
(p.10)
Arctic Ice Record Low
As of late August, the ice in the Arctic covers the least area it has in three decades
(p.11)
Demystifying Ocean Methane
Chemical Oceanography: Microbes that make methylphosphonate constitute a new biosynthetic pathway
(p.11)
Chemists Gather In Prague
International: European Association for Chemical & Molecular Sciences holds fourth biennial conference
(p.12)
Romney To Focus On Fossil Fuels
Energy Policy: Plan would end subsidies for renewable energy, makes no mention of climate change
(p.12)
DuPont To Divest Automotive Coatings
Planned sale to private equity firm follows acquisitions in biobased materials
(p.13)
Wiring Up Living Tissue
Sensing: Merging biology and electronics could lead to smart implants and prosthetics
(p.13)
Departments
Business
Developing a drug for a neglected disease economically involves wide-reaching partnerships
(pp. 26-27)
Repurposed labs to work on drug discovery and metabolic testing
(pp. 40-43)
Transgenics Firms Struggle To Keep Going
Making transgenic animals to produce drugs has matured, but few products have come to market
(pp. 34-38)
Universities Visit The Business Model
Fee-for-service contracting rises in an opportunistic approach to drug discovery research
(pp. 30-33)
Increasingly discouraged by genomics-based discovery, researchers revert to whole-cell screening for tuberculosis treatments
(pp. 15-24)
Concentrates
(pp. 28-29)
(pp. 28-29)
- Private Equity Bids For TPC
- Germany’s Q-Cells Going To Hanwha
- Sapphire Reports Big Algae Harvest
- BASF Ups Global Glycol Capacity
- PDVSA Investigates Venezuelan Blast
- Airbus, Aemetis Plan Jet Fuel From Oils
- Trash-To-Sugar Process Explored
- Tessenderlo Takes Strategic Actions
- DuPont Insecticides Going To Syngenta
- Monsanto And Alnylam Join For Agriculture
- Hospira Will Acquire Indian API Facility
- Aesica Teams Up With Bradford University
- Former Roche Exec To Lead AstraZeneca
- Business Roundup
ACS News
Awards(p.78)
(p.78)
- Thomas Degnan Receives Ciapetta Lectureship
- Carbohydrate Division Presents Awards
- Catalysis Award Goes To Merck Team
- 2012 ExxonMobil Solid-State Fellowship To Michael Shatruk
- Schieberle Wins Agricultural & Food Chemistry Award
- WCC Names Rising Stars
Government & Policy
Congress Rethinks Reach Of Ethics Law
Scientists oppose financial disclosure requirements of insider-trading ban
(pp. 50-54)
White House Promotes Science Volunteerism
Office of Personnel Management asks federal scientists, engineers to volunteer
(p.56)
Mapping Nanotech Drugs’ Landscape
FDA struggles to identify products, optimize review process
(pp. 46-48)
Concentrates(p.44)
(p.44)
- Fuel Standard Raised
- Energy Department Targets Solar Tech
- Group Asks EPA To Curb Ocean Pollution
- Denmark Proposes Ban On Phthalates
- Patent Office Picks Site In Denver
Education
Boot Camp For Professors
Workshop for starting chemistry faculty focuses on developing teaching skills
(p.76)
Instructors aim to make science more relevant for undergrads not majoring in the subject
(pp. 74-75)
Science & Technology
Edgar Fahs Smith Remembered
ACS Meeting News: University of Pennsylvania chemist fostered electrochemistry, ACS, and chemical history
(pp. 72-73)
Pesticides Trend All-Natural
ACS Meeting News: Chemists discuss the growing role of natural products in developing new pesticides
(pp. 64-67)
Tweaks Boost Protein Stability
ACS Meeting News: With new methods to modify protein backbones, chemists probe what makes proteins stable
(pp. 68-71)
Extracting Uranium From Seawater
ACS Meeting News: Massive marine supply of metal drives researchers to design selective, durable sorbents
(pp. 60-63)
Concentrates(pp. 58-59)
(pp. 58-59)
- New Phosphinidene Transfer Reagents
- New Chemically Modified Single-Stranded RNA Turns On RNAi Pathway
- Biomimetic And Extreme Surface-Area Frameworks
- Coating Helps Nanoparticles Penetrate Brain Tissue
- Reaction Yields Flat Hydrogen-Coated Surfaces
- Method Detects Zeptomoles Of TNT
- Droplets From Mold May Seed Rain Forest Aerosols
- Urban Soot Particles May Warm Climate Less Than Believed
Career & Employment
Perfect Your Presentations
Tips for scientists preparing a talk about their work
(p.80)
Newscripts
Fruitilicious Chocolate, Gibbons Of The Opera
Editor's Page
Curiosity On Mars
Letters
LettersLetters(pp. 6-7)
Letters(pp. 6-7)