March 24, 2014 Issue | Chemical & Engineering News
 
 
 
Copyright © 2014 American Chemical Society
 

March 24, 2014 Issue

Volume 92, Issue 12

March 24, 2014 Issue, Vol. 92 | Iss. 12

Changing The Channel

Human genetic studies point drugmakers to a specific sodium channel target for painkillers
By Bethany Halford
(pp. 10-14)
Features
Government & Policy

Budget Blues

President Obama’s 2015 R&D budget request doesn’t keep up with inflation (pp. 26-29)
Science & Technology

Living Up To The Process Challenge

In a typical day, process chemists select reagents, pore over synthetic routes, think about safety, and manage costs (pp. 30-33)
Back Issues
 

News of the Week

Chemists Convene In Dallas

ACS Meeting News: ‘Chemistry & Materials for Energy’ was national conference’s theme
(p.4)

Stem Cell Memories

ACS Meeting News: Growing stem cells in stiff or soft environments influences their future differentiation
(p.5)

Trinseo Makes Second Attempt To Go Public

Polymers producer formerly known as Styron files plans to pay down debt
(p.5)

ACS Meeting News: Reagent Assembles Ring Motifs Common In Drugs

Method builds medium-sized nitrogen heterocycles with challenging substitution patterns
(p.6)

California Targets Products

Regulation: State proposes elimination of certain chemicals or substitution with safer alternatives
(p.6)

Certain Pet Flea Collars’ Days Are Numbered

EPA, two manufacturers agree to phase out products that contain propoxur, a neurotoxin
(p.7)

Role Of Folded DNA Revealed

ACS Meeting News: Study shows i-motifs and related hairpins activate or repress gene expression
(p.7)

Prenatal Vitamin A Essential For Offspring Immune Health

Reproductive Medicine: A healthy fetal immune system in mice depends on mothers ingesting the vitamin
(p.8)

FDA Bans Another Indian Drug Plant

Generics: Quality problems plague Indian producers
(p.9)

Spray-On Polymer Mats Seal Surgical Incisions

Biomaterials: Researchers apply mats of biodegradable nanofibers directly onto tissues using a commercial airbrush
(p.9)
 

Departments


Business

Licensing Out

Eli Lilly & Co. tries to get creative about cultivating compounds that might otherwise collect dust
(pp. 22-23)

ARPA-E Summit Put The Spotlight On Energy Innovations

Natural gas, funding concerns shadowed technologies that promise low- or no-carbon energy
(p.24)

Restructuring For Real In Japan

Pressured by high costs and a shrinking home market, producers are getting serious about slashing unprofitable businesses
(pp. 18-20)
Concentrates(pp. 16-17)
  1. Wacker Eyes U.S. Expansion
  2. Dow Earmarks More Units For Sale
  3. Tedlar Covers Goodyear Blimp
  4. KiOR In Desperate Financial Straits
  5. Evonik Sets Facility For Novel Methionine
  6. LG Chem Buys U.S. Filtration Firm
  7. Air Liquide Spends On R&D In France
  8. Sensient Slugs Back At Activist Investors
  9. BMS Inks Deal With Five Prime
  10. Biogen, Atlas Give Ataxion Booster Shot
  11. Thermo Fisher Buys Prionics
  12. MedImmune Adds Two Academic Partners
  13. Japanese Drug Firms To Share Compounds
  14. Business Roundup

ACS News

Mentoring New Faculty—It Really Works!

What you didn’t learn in graduate school about being a professor
(p.36)
Awards(p.37)
  1. Biological Chemistry Awards Presented
  2. Nominations Sought For ACS Fellows
  3. 2014 Award For Creativity In Molecular Design & Synthesis
  4. Nominations Sought For Young Innovator Award
  5. High School Teaching Grants Available
  6. 2014 Norris Award Seeks Nominations
  7. Nominations Sought For Nichols Medal

Government & Policy

Budget Blues

President Obama’s 2015 R&D budget request doesn’t keep up with inflation
(pp. 26-29)
Concentrates(p.25)
  1. White House, AAAS Each Roll Out A Climate Initiative
  2. Eastman Kodak To Pay For Cleanup
  3. Bill Aims To Speed Sunscreen Approval
  4. CSB Releases Video On Tesoro Accident
  5. Shippers Push For Rail Rate Rule Change

Science & Technology

Changing The Channel

Human genetic studies point drugmakers to a specific sodium channel target for painkillers
(pp. 10-14)

Dynamics Determine Enzyme Selectivity

Biosynthetic protein may steer a reaction after the transition state to home in on a single natural product
(pp. 34-35)

Living Up To The Process Challenge

In a typical day, process chemists select reagents, pore over synthetic routes, think about safety, and manage costs
(pp. 30-33)
Concentrates(pp. 28-29)
  1. Taking Cues From Nature En Route To Paclitaxel
  2. Building Tissue Layer By Layer
  3. Papermaking Waste Could Fix BPA Problem
  4. Teaching Zinc A New Trick
  5. Drug Delivery System May Treat Common Cattle Infection
  6. Lactone Helps Push Carbon Dioxide To Couple With Olefins
  7. Gut Microbes Bring Out Best In Cocoa
  8. For Drug Analysis, Paper Spray MS Is Faster Than LC/MS

Newscripts

Chemically Inspired Music, Tuneful Apathy

(p.40)

Letters

Letters(pp. 2-3)
  1. More About Indian Generic Drug Manufacturers
  2. Commit To Advocacy
  3. No Retreat From Reform